First, buying on a single salary is always difficult, because you are competing primarily against dual-income households.

Second, the problem seems to be chasing the hottest job markets. Those places are often unaffordable, because there is too much money floating around. They are good for people near the top, who can get very high compensation, as well as those near the bottom, who are happy to accept any job. People in the middle often find better deals in places with fewer opportunities and lower costs of living.