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A comment on Pre-exposure to mRNA-LNP inhibits adaptive immune responses in mice. Parent comment

Re:Pre-exposure to mRNA-LNP inhibits adaptive immune respons... by jaywalk on Tuesday September 13, 2022 @10:32AM (#32824762)
> mRNA was in studies prior to COVID, its not like we made it up in 3 weeks.

Part of the reason it was in studies for so long is because it kept failing. But in two weeks (seriously! That's straight from Moderna) they were able to button everything up and make it work for Covid.

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Re:Pre-exposure to mRNA-LNP inhibits adaptive immune respons... by ceejayoz on Tuesday September 13, 2022 @10:56AM (#32825092)
> Part of the reason it was in studies for so long is because it kept failing.

"How could ten years of development possibly generate a working product?" is a take, I suppose.

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Re:Pre-exposure to mRNA-LNP inhibits adaptive immune respons... by mrguyorama on Tuesday September 13, 2022 @01:48PM (#32827788)
The only reason it wasn't developed before COVID was because it wasn't a profitable improvement over other styles of vaccines. It was literally a business decision to not develop it more.
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