Undermining the whole concept of "science".

Perhaps with some justification, perhaps not. But if replication is impossible because of "irreducible complexity" (seems to be the argument?) then why bother with science at all?

Things are not that bad. But in some fields other approaches may be more productive.

For example clinical medicine may have more to contribute than scientific medicine. Psychological studies in particular are notorious for being impossible to replicate. Does not mean we should give up on psychology. It does not have to be science to be useful