Sure, but why on earth would any tourist choose to stay at some off site tourist hub? The whole point of visiting a historic city like say Lisbon, is that you get the stay in an historic city, not some modern off site tourist hub where you get to take a crammed full tourist bus to the centre..

Or would you propose strict accompanying zoning laws with strict enforcement? I think that would meet stiff resistance from property owners but would be feasible. I do think all of this would make the destination much less attractive to visit though so it really comes down to how much you want/need the tourists.