U.S. life expectancy drops sharply, the second consecutive decline

Re:U.S. life expectancy drops sharply, the second consecutiv... by jldugger on Wednesday August 31, 2022 @09:37PM (#32670754)

The good news is that maybe we got it backwards, in at least some of the cases[1]:

> Higher fasting insulin and higher c-reactive protein confound the association between BMI and the risk of all-cause mortality. The increase in mortality that has been attributed to higher BMI is more likely due to hyperinsulinemia and inflammation rather than obesity.

[1]: https://www.nature.com/articles/s41366-022-01211-2

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Re:U.S. life expectancy drops sharply, the second consecutiv... by losteric on Wednesday August 31, 2022 @09:59PM (#32670934)

> The increase in mortality that has been attributed to higher BMI is more likely due to hyperinsulinemia and inflammation rather than obesity

Not sure I understand this sentencen. Are they saying hyperinsulinemia and inflammation are independent of obesity? Both symptoms of <X>?

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Re:U.S. life expectancy drops sharply, the second consecutiv... by orwin on Thursday September 01, 2022 @04:14AM (#32673485)

What i understood (this is quite new and i haven't had time to research this): Some nutritionists and medical practitioner think that most obesity (the >35BMI kind) are caused by hormones (some gland inflammation, like i said i didn't researched this) or prediabetes. Hence why European immigrants are not hit the same as natives in the US, as phylogenetic have quite an impact on hormones production.

This was an old theory and some recent research proved that at least it needs to be investigated more seriously.

In general hormones effect on human development, while being quite an active field, seems to be still underfunded or at least more ignored than it should be.

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