Just today I saw part of a BBT rerun on German TV: The guys camp out in some lodge, together with the lodge's owner. That owner is also a brilliant(?) scientist, living alone in the lodge. I think he is from Germany, but that might differ depending on the localisation. He and his wife send each other cards once per year, for their respective birthday. Well, turns out most years, because this year he forgot it (Sheldon later realizes that in fact Amy is more important to him than science). Anyway, he asks them if they know the difference in taste between (wild) rabbit and squirrel, and since the guys say they don't, "well, then we'll have bunny today" and leaves the lodge with his rifle. The guys then leave while he is hunting, with Sheldon commenting "I know the difference, I'm from Texas".

So, as a German, should I be offended because of the squirrel/rabbit thing? Should Texans be offended? What about the career over partner theme, is that insensible to Germans divorcing due to career-induced burnouts?

No, it's just a joke. I don't believe anyone would think we ate squirrel, and I don't believe Texans do. (However, rabbit is in fact eaten around here. It's also a meat in France (who are famous for their cuisine) and... China. Says the Internet. But around here rabbit is more a delicacy, often for Easter or other special occasions; personally I think I haven't eaten rabbit meat in nearly a decade. Also, the rabbits-for-eating are large animals, not bunnys. Those are adored and loved as pets).