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Re:Psychedelic drugs take on depression by FollowingTheDao on Friday August 26, 2022 @06:11PM (#32613338)
Yes, this. IMHO, there are two type of depression, both immune mediated, and both drive my glutamate/GABA imbalance. One is high glutamate the other is high GABA, either effecting different region of the brain.

This imbalance affects serotonin and norepinephrine release.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8311508/

And this change is mediated by the immune system. Glutamate is now known as an immunomodulator.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997749/

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