"They cannot continue focusing on software running on general-purpose CPUs but must re-orient themselves towards specialized hardware."

In other words, mainframes.

This trend has already started in general purpose computing - just look at what Apple is doing with their SOCs - dedicated cores for specific functionality as well as their own I/O engines for storage, all integrated into their SOC. Typing this on an M1 Macbook Pro, I can verify that this approach does indeed have a plethora of performance and efficiency benefits!