Indeed. Interestingly, psychedelics (mushrooms, LSD) work wonderfully for me, but cannabis is typically a bad experience (anxiety, nausea, no attention span, racing thoughts). Every brain is wired differently.

-- THC is also a lot wider ranging than typical psychedelics - a dose of LSD tends to be a does of LSD - from my experience a trip on AL-LAD or LSD are basically same - also true with PE vs Golden Teachers Psilocybin - however - strands and doses of sativa vs indica can differ massively - won't smoke Jack the Ripper as it's just not a good time for me --

in my experience, nausea tends to be dose-dependent...and edibles are the most efficient way the human body can metabolize the THC family, so proper dosing is much more important for edibles. if you're smoking, and have zero tolerance, a single small toke is probably advised. at least then any discomfort won't be terribly long-lived.

manic symptoms vs. depressive symptoms can definitely be linked to strain, and the balance of constituent psychoactives...of which there are plenty. ask a reputable bud tender for sleepy weed and i wager your experience might be more pleasant.

It seems sativa vs indica is a made up “system” and the actual effects very much depend on each individual.

If we’re works for you, great. If it doesn’t, something else will.