My understanding is that uMatrix is a bit different. By default, it will block just about all third-party requests. It can sometimes be a pain to manage, in particular for sites with many redirects and an absurd number of domains. I'm thinking Azure/Office365.

It's not a full replacement for uBO either because it won't attempt to do anything fancy to block ads specifically.

However, uMatrix is no longer maintained. Its GitHub page [0] says the project has been archived. I'm still using it, don't know whether there are any risks in doing so.

[0] https://github.com/gorhill/uMatrix