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Re:New antibody neutralizes all known SARS-CoV-2 variants in... by johnchristopher on Thursday August 18, 2022 @01:18AM (#32505592)
> by giving human populations such artificial resistances (non-live vaccines) we run the risk of selecting for viruses that are even harder for even our own immune systems to detect and destroy

That'd be a valid question if we didn't ready have non-live vaccines with very good proven track records for polio, hepatitis, the flu, etc.

> Current Covid strains don’t seem all that bad, basically everyone I know has been infected now.

And here comes the covid denial argument. Relentlessly repeating the same loaded arguments again and again.

> Might we run the risk of making things worse at this point?

Yeah, but what about wind turbine's rare earth ? It's really polluting ! And what if climate change has more benefits than problems once we have adapted, uh ?

Re:New antibody neutralizes all known SARS-CoV-2 variants in... by ehvatum on Thursday August 18, 2022 @03:24AM (#32506391)
To be fair, you are stigmatizing someone for offering a correct observation (that the successive COVID variants have proven less debilitating and deadly) and for asking a question that must be on many people’s minds: can monoclonal antibody administration promote resistance analogous to bacterial antibiotic resistance?

Be aware that live virus vaccines are certainly not monoclonal antibody injections.

As well, rather than spending your mental energy developing excuses to dismiss, why not think on the subject at hand? You should wonder why this mouse model produces broadly neutralizing antibodies in response to COVID spike proteins while the human immune system does not.

That’s a bit interesting to the subject of COVID, isn’t it? Certainly more so than windmills and politics.

Re:New antibody neutralizes all known SARS-CoV-2 variants in... by johnchristopher on Thursday August 18, 2022 @05:21AM (#32507156)
> To be fair, you are stigmatizing someone for offering a correct observation (that the successive COVID variants have proven less debilitating and deadly) and for asking a question that must be on many people’s minds: can monoclonal antibody administration promote resistance analogous to bacterial antibiotic resistance?

No, I am singling out another comment which spreads doubts and denial by hiding them among good faith arguments. For instance:

> (that the successive COVID variants have proven less debilitating and deadly)

Doesn't mean it's not debilitating and deadly.

> basically everyone I know has been infected now.

And I haven't and neither my best friend nor my parents did. But my brother did and another friend did. Guess which one is complaining 6 months later of symptoms that are not going away ?

> As well, rather than spending your mental energy developing excuses to dismiss, why not think on the subject at hand? You should wonder why this mouse model produces broadly neutralizing antibodies in response to COVID spike proteins while the human immune system does not.

> That’s a bit interesting to the subject of COVID, isn’t it? Certainly more so than windmills and politics.

I believe Covid was and is still dangerous and not to be taken lightly because "most people I know has been infected and successive strains are less deadly" (the last one being also dodgy since it might as well be less deadly for an individual but more deadly for a population if it infects much more people, anyway...). That's as worthy to discuss as the core of the submission is.

Re:New antibody neutralizes all known SARS-CoV-2 variants in... by jjcon on Thursday August 18, 2022 @08:43PM (#32516534)
> by hiding them among good faith arguments

It is literally in the HN rules that you are supposed to assume good faith, not concoct false attributions of intent and conspiracy. I did not intend to hide anything, I was earnestly asking a question (clearly shared by plenty others in this post). It should not upset you this much. I apologize for anything triggering to you that I said, that wasn't my intent.

https://news.ycombinator.com/newsguidelines.html

Re:New antibody neutralizes all known SARS-CoV-2 variants in... by johnchristopher on Friday August 19, 2022 @03:02AM (#32518218)
> It should not upset you this much.

The question pertaining to the core of the submission does not upset me, nor do I find it in bad faith (that one I assume good faith since it's legitimate).

> Current Covid strains don’t seem all that bad, basically everyone I know has been infected now.

This, does. Because it has nothing to do with the submission but all with covid minmizing thrown in after a legitimate question.

> I apologize for anything triggering

and

> Assume good faith - its in the rules friend (https://news.ycombinator.com/newsguidelines.html)

This wording (emphasis mine) tells me all there is to know about why I shouldn't explain myself to you.

Re:New antibody neutralizes all known SARS-CoV-2 variants in... by jjcon on Friday August 19, 2022 @05:53PM (#32526427)
What exactly does that tell you? I called you friend and apologized if I upset you (which you have acknowledged I did by comparing current strains to the original and making the judgement call that the current strains in our current situation aren't so bad... again relatively). I'm genuinely not sure what is wrong with any of that, perhaps a language barrier thing, apologies again in any case.
Re:New antibody neutralizes all known SARS-CoV-2 variants in... by cas14655 on Friday August 19, 2022 @05:58AM (#32519173)
> This, does. Because it has nothing to do with the submission but all with covid minmizing thrown in after a legitimate question.

Question: how low does the IFR have to be so we can call a disease "not so bad" without "minimizing" it?

Re:New antibody neutralizes all known SARS-CoV-2 variants in... by johnchristopher on Saturday August 20, 2022 @02:18PM (#32534069)
Question: how long does it take for that other famous disease to show the long term effects of t-cells exhaustion ?
Re:New antibody neutralizes all known SARS-CoV-2 variants in... by cas14655 on Tuesday August 23, 2022 @06:18AM (#32562681)
Are you getting at potentially unknown long term effects of COVID infection?
Re:New antibody neutralizes all known SARS-CoV-2 variants in... by jjcon on Thursday August 18, 2022 @03:17AM (#32506347)
Where did I deny Covid? I simply asked if stronger vaccines could lead to stronger viruses and make things worse than they already are
Re:New antibody neutralizes all known SARS-CoV-2 variants in... by johnchristopher on Thursday August 18, 2022 @05:24PM (#32515096)
No, you did not simply ask that. You also said Covid is now not that bad and implied it's okay to be infected since everyone you know has been infected now.
Re:New antibody neutralizes all known SARS-CoV-2 variants in... by jjcon on Thursday August 18, 2022 @08:29PM (#32516428)
Assume good faith - its in the rules friend (https://news.ycombinator.com/newsguidelines.html)

If that is what you took from my comment I apologize that isn't what I intended to convey at all. I did however intend to ask a question about the topic at hand (broader vaccines) in our current situation which is categorically improved relative to early covid