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A comment on Ask HN: What's the next big thing that few people are talking about?. Parent comment

Re:Ask HN: What's the next big thing that few people are tal... by cauthon on Monday August 08, 2022 @01:42PM (#32388620)
Yes, I think height is a heritable trait.

Understanding whether the model is capturing biology is critical when thinking about applying it to IVF. If the model is primarily capturing socioeconomic correlates, those factors will (in most cases) be fixed for all embryos from a given pair of parents. The PRS needs to be weighting _biological_ risk conditioned on a fixed environment if its to be used ethically in this context.

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Re:Ask HN: What's the next big thing that few people are tal... by s1artibartfast on Monday August 08, 2022 @02:26PM (#32389123)
What are your requirements for ethical use?

In what case are you expecting the purchasers to be harmed? It seems reasonable to screen for the other factors as well if a correlation exists.

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