Re:AlphaFold reveals the structure of the protein universe
by biomcgary on Thursday July 28, 2022 @01:20PM
(#32267439)
Organisms, yes. Individual genes within an organism may have no sequence identity to genes in other organisms (outside of what you would expect at random). See: https://en.wikipedia.org/wiki/Orphan_gene
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Re:AlphaFold reveals the structure of the protein universe
by dekhn on Thursday July 28, 2022 @01:24PM
(#32267499)
Yes, that's what I thought. I worked with m. genitalium and we were always looking for proteins that had no homology or no existing structure (https://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.20...)