I have a very sensitive stomach; I get an upset stomach (watery stools) and pimples all over my forehead and head when I have coffee. With cold brew, (if made properly), I do not get any of this. So there is definitely some difference in the chemical constituents of hot-coffee vs cold-brew-coffee. Some other papers state less caffeic acid and less quinic acid.

https://www.nature.com/articles/s41598-018-34392-w