If you're staying at the Sheraton, there may be negligence but you can be confident that there will be proper insurance.
Much more common than a fire would be theft. My friend was staying at the Shangri-La in Paris for his honeymoon. The porter took his bags while he was checking in, and their bags were stolen right out front the hotel.
The hotel apologized profusely, upgraded them to a very nice suite, and they got something like EUR 5000 for their belongings. He had a camera but mostly it was just their clothes (and suitcases) that they had to replace.
Hotels are like the opposite of Comcast or United. There is a lot of competition. They are literally called the Service Industry. AirBnb's offer a lot that hotels don't (charm, locations, potentially cost), but security and consistency is not it.
It's not like there's zero chance of negligence at a proper hotel, but yeah the odds should be better.
I'm reminded of an incident ages ago when I was renting a modern townhouse in a large corporate complex where they were arranged like duplexes with shared garage walls. My gf at the time had fallen asleep immediately after starting one of those Duraflame logs without opening the flue. She and our cats nearly died from smoke inhalation.
The units were all on a centralized smoke detector/fire alarm system powered by in-wall wiring that we weren't responsible for. We didn't know it at the time, but someone had unplugged all of the detectors so no alarms went off while her and the cats came dangerously close to dying in the buttoned up space. I came home to find her and the cats sitting on the front stoop, all coughing and sooty. The interior was all blackened with smoke damage.