I found the author to have cherry-picked and poorly-cited information earlier on in the book when talking about antidepressants, and then a complete lack of rigor when discussing the various lost connections. I think he has a point, but I just didn't find it very well done, and as another comment here has quoted: > Other clinicians say, however, that the notion of depression being because of a simple chemical imbalance is outmoded anyway, and that antidepressants remain a useful option for patients alongside other approaches including talking therapies.

It is also notable that the author has had plagiarism issues and other questionable behaviors in the past: https://en.wikipedia.org/wiki/Johann_Hari#Plagiarism_and_fab...

There's also the driving our novelty seeking brains into overdrive with all kinds of artificial stimulants, including this very forum.

I recommend “The Cult of Pharmacology,” which long ago characterized this serotonin theory as bio-babble reductionism

Sounds like Kaczynski’s “power process” in Industrial Society