Hard drives (both rotary and SSD; floppies [1] and CDs [2] also) are also manufactured according to base-2 addressing. They are low-level formatted at the factory in sectors which are power-of-2 sizes. [3] This has been true for at least 40 years. [4]

[1] https://en.wikipedia.org/wiki/Disk_formatting#Low-level_form...

[2] https://en.wikipedia.org/wiki/CD-ROM#Sector_structure

[3] https://en.wikipedia.org/wiki/Disk_formatting#Low-level_form...

[4] https://en.wikipedia.org/wiki/Disk_sector