An attacker would need to do some quite invasive hardware tampering to get a third party hypervisor to work on a system secured like that.
Furthermore, preventing hypervisor detection requires constant updates if the OS itself is configured to check for the presence of a hypervisor. There's a constant arms race going on between security researchers and cybercriminals who don't want their malware to trigger on analysts' machines, many of which use virtualization to easily reset the system back to a known, secure state. Every time malware comes up with a new method of detection your evil hypervisor needs to be patched to fake that stuff too or you risk detection next time the OS updates its detection algorithms.
See also: https://forum.qubes-os.org/t/verified-boot-on-qubes-a-lofty-...