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Re:FDA approves first systemic treatment for alopecia areata by meremortals on Tuesday June 14, 2022 @02:57PM (#31744262)
This is great, but note that Alopecia Areata is different from male pattern baldness
Re:FDA approves first systemic treatment for alopecia areata by LewisVerstappen on Tuesday June 14, 2022 @03:46PM (#31745017)
Yeah, but there is Finasteride for male pattern baldness which has fantastic results and is incredibly cheap (I got a 3 month supply for $12).

A 10 year study published by the Tokyo Medical Clinic of finasteride carried out in Japan found that more than 99 percent of men with male pattern baldness experienced no worsening of their hair loss during treatment [1]

Tons of additional clinical evidence showing that Finasteride works.

[1] - https://www.researchgate.net/publication/337105943_Long-term...

Re:FDA approves first systemic treatment for alopecia areata by skrtskrt on Tuesday June 14, 2022 @03:54PM (#31745148)
The key being that it doesn't give any hair regrowth in the vast majority of people, so you have to get people taking it before they see much balding, which is an interesting challenge - why worry about something you can barely see or notice until it's already a problem?

There are ad campaigns from male order providers such as Hims and Keeps around this, I wonder how effective they are.

I take it, and it stopped the balding progression as far as I can tell, but I had to get an FUE hair transplant to get some lost hair back.

Re:FDA approves first systemic treatment for alopecia areata by LewisVerstappen on Tuesday June 14, 2022 @03:58PM (#31745218)
> why worry about something you can barely see or notice until it's already a problem?

So, you measure hair loss with the Norwood scale. You don't go from 100% hair to bald spots immediately.

First, you'll see diffuse thinning where the thickness of your hair drops significantly.

In the first stages of diffuse thinning, it won't be apparently to 99% of people that your hair is thinning but you'll immediately notice when you take a shower / apply shampoo (it's really obvious when your hair is wet).

I'd say that's when most men realize they're losing their hair and that's when they should get on Finasteride.

Re:FDA approves first systemic treatment for alopecia areata by nsxwolf on Tuesday June 14, 2022 @06:18PM (#31746729)
It may still be too late at that point. In my experience people who care about a man's hair (women, mostly) see hair loss as a binary thing - you either have a full head of hair, or you're balding. They don't see a guy in the earliest stages of hair loss and say "Oh, he's got a pretty decent Norwood score!", they say "he's bald".

I've known two women that mentioned they'd rather date a man with a full head of hair who shaves his head than a balding man who shaves his head. I pressed it as far as asking "Well, what if they keep shaving it for life?" Same answer.

Re:FDA approves first systemic treatment for alopecia areata by skrtskrt on Tuesday June 14, 2022 @06:41PM (#31746925)
It also depends on your head shape, I see a lot of men who are very good looking still with a fair amount visible recession, and they do quite well with their dating life.

Personally I just felt like the relatively small amount of recession I had looked terrible on me because I already had a tall forehead to begin with, and I'm still in my 20s.

Re:FDA approves first systemic treatment for alopecia areata by cguess on Tuesday June 14, 2022 @09:09PM (#31748001)
To be honest: most women care way less than you think. Personality trumps hair 95% of the time. A good barber can make you look good even with thinning hair, fine someone you like, stick with them, and tip well.
Re:FDA approves first systemic treatment for alopecia areata by hoveringcto on Tuesday June 14, 2022 @11:18PM (#31748747)
Keep in mind Finasteride isn't for recession, but for loss at the crown, though it is known to work elsewhere - it isn't approved for that.
Re:FDA approves first systemic treatment for alopecia areata by usehand on Tuesday June 14, 2022 @11:53PM (#31748937)
That is not true at all. I have been taking finasteride for years, since I noticed a little recession around my temples and a small loss of density around the front. I noticed it because I know my hair well.

The only other people that might actually be able to tell it are my parents. Except for that, every other person to whom I mention I use finasteride and minoxidil says something of the sort: "wtf, you have a full, dense head of hair, why would you take anything?".

Re:FDA approves first systemic treatment for alopecia areata by amyjess on Tuesday June 14, 2022 @09:49PM (#31748235)
I think it's more likely that if someone's in the earliest stages of balding, people are more likely to say "he has a widow's peak" than "he's bald". Until someone hits Norwood stage 4, there's no visible bald spot, just recession around the temples.
Re:FDA approves first systemic treatment for alopecia areata by JamesBarney on Tuesday June 14, 2022 @07:31PM (#31747325)
I don't think that's true. Nicholas Cage in Con Air is pretty obviously balding, but no one would say he's bald.
Re:FDA approves first systemic treatment for alopecia areata by Hellbanevil on Tuesday June 14, 2022 @08:02PM (#31747584)
He's been wearing different hair pieces for years.

For some reason actors get a pass.

Keven Smith was tired of Bruce Willis talking about his weight. So, in a friendly guy's banter, he started calling him Cue Ball on a set.

Everyone said Bruce can make fun of us, but never mention his hair.

Whomever did Elon Musk's hair line did a good job.

Re:FDA approves first systemic treatment for alopecia areata by kadoban on Wednesday June 15, 2022 @02:15AM (#31749692)
> For some reason actors get a pass.

Being able to spend a lot of time and money to look good does wonders to help take the sting out of whatever physical flaws one might have.

Not to mention most of them are generally attractive which also helps in a similar way.

Re:FDA approves first systemic treatment for alopecia areata by bennysomething on Tuesday June 14, 2022 @04:58PM (#31745991)
I've been on finastride for about 12 years. I'm never sure if it's working or not. Scared to stop!

How well did the hair transplant work?

Re:FDA approves first systemic treatment for alopecia areata by skrtskrt on Tuesday June 14, 2022 @06:33PM (#31746864)
Never stop!

Hair transplant worked really well. Natural-looking hairline, which is the most important part. You'll see a lot of before and afters where the hairline looks like a Lego block hair piece was snapped into place - choose your doctor carefully here.

You'd only notice if you're looking really closely, where you'll see that the hairs are quite a bit thicker, as they were transferred from the back of my head where everyone's hairs are thick, but I have especially thick hair in general.

Re:FDA approves first systemic treatment for alopecia areata by bennysomething on Wednesday June 15, 2022 @04:08AM (#31750333)
Thanks for this
Re:FDA approves first systemic treatment for alopecia areata by 01100011 on Tuesday June 14, 2022 @06:53PM (#31747008)
One thing I think worth mentioning is that you should anticipate having to get multiple transplants if you expect to have much future hair loss. I just saw a guy a few weeks ago who had gone mostly bald on top but had an obvious row of hair across his hairline. It looked like he had gotten a transplant early on and then didn't continue as his hairloss progressed.
Re:FDA approves first systemic treatment for alopecia areata by mywittyname on Tuesday June 14, 2022 @03:58PM (#31745212)
There's surgery to replace the lost hair (with hair moved from somewhere else, granted). It's certainly much more expensive than catching it early and treating it with minox or whatever, but it's within the reach of many people (<$10k).
Re:FDA approves first systemic treatment for alopecia areata by nayaketo on Wednesday June 15, 2022 @12:07AM (#31749005)
What happens to the old area from where the hair is taken?
Re:FDA approves first systemic treatment for alopecia areata by hiram112 on Wednesday June 15, 2022 @02:48AM (#31749885)
It's taken in small strips from the back and sides of the scalp which, for whatever reasons, aren't prone to the mechanisms causing male pattern baldness on the top of the head and hairline. So theoretically those areas where the hair was mined will now be thinner, but they do it in a manner that you'll never notice the decrease in hair in those areas.
Re:FDA approves first systemic treatment for alopecia areata by bbarnett on Tuesday June 14, 2022 @05:07PM (#31746113)
I heard from a barber, that despite claims hairs from the back of the head are different follicles, and won't die off, this is all lies and marketing bs.

So you need endless treatments, or else take testosterone blockers.

Re:FDA approves first systemic treatment for alopecia areata by skrtskrt on Tuesday June 14, 2022 @06:37PM (#31746888)
Well

1. even back of head hair thins eventually in balding people, but generally many decades later than the front or crown. By the time you're losing that hair, you're probably a lot older and care much less

2. taking finasteride indefinitely is supposed to drastically slow or stop further thinning or loss. Of course as in point 1, you're probably going to lose that battle eventually, but again you'll be much much older when the damage gets serious than you would have been otherwise

Re:FDA approves first systemic treatment for alopecia areata by rjh29 on Tuesday June 14, 2022 @05:28PM (#31746307)
And you continue to recede so you will need follow-up treatments for that. If you're too far gone it's just not practical.

It's a meme at this point, but for most people shaving their head is the right option.

Re:FDA approves first systemic treatment for alopecia areata by maerF0x0 on Tuesday June 14, 2022 @04:07PM (#31745348)
iirc there's a largely genetic component to it, so one could simply proactively take it if they carry the genes. But the side effects can be unfortunate (depression, libido) . Seems like topical is better than oral.
Re:FDA approves first systemic treatment for alopecia areata by rjh29 on Tuesday June 14, 2022 @05:27PM (#31746297)
I took it way too late and it didn't really help. I shaved after and I'm really happy with that decision.
Re:FDA approves first systemic treatment for alopecia areata by meremortals on Tuesday June 14, 2022 @03:54PM (#31745154)
Same. Not much, if any, regrowth
Re:FDA approves first systemic treatment for alopecia areata by lolwutf on Tuesday June 14, 2022 @07:33PM (#31747346)
Leaving this here for other men who might stumble on this: Oral finasteride drives your DHT way down. However, driving DHT down is essentially the binary goal of stopping hair loss.

And that's all fine and good, but having 'just enough' DHT is important for good health. (Psychology, sexual function, etc)

If you're on finasteride, do yourself a favor and consult with a TRT ('low T') doctor, have your DHT level tested, and consider modulating your finasteride dosage according to its effect on your DHT level.

A good balance is worth working towards. Don't blindly take finasteride without keeping an eye on its effects to your DHT.

Re:FDA approves first systemic treatment for alopecia areata by agent008t on Tuesday June 14, 2022 @05:26PM (#31746292)
Given the potential serious, life-changing adverse effects that persist even after stopping use - no thanks. Just cut your hair short / shave your head.
Re:FDA approves first systemic treatment for alopecia areata by bitwize on Tuesday June 14, 2022 @08:07PM (#31747613)
Minoxidil is highly, HIGHLY toxic to cats. Pregnant women shouldn't handle finasteride because the hormonal effects could cause them to lose the baby. I decided I'd rather go bald than put any cats or women in my home, or my unborn child, at risk. That was before I learned about the long-term detrimental sexual side effects of finasteride.
Re:FDA approves first systemic treatment for alopecia areata by Grazester on Tuesday June 14, 2022 @10:06PM (#31748331)
I wouldn't worry about Minoxidil with cats unless you plan to feed it to them. It's not different with dogs and chocolate.
Re:FDA approves first systemic treatment for alopecia areata by LewisVerstappen on Tuesday June 14, 2022 @11:51PM (#31748926)
Same thing with pregnant women and Finasteride. Doesn't really matter unless you plan on feeding your pregnant wife your finasteride pills.
Re:FDA approves first systemic treatment for alopecia areata by rjh29 on Tuesday June 14, 2022 @05:29PM (#31746323)
Maybe in the 70s/80s it was weird to be bald, but there are so many bald people now, it's like whatever. If you think I'm ugly or you're not into it fine, but there are plenty of women who are.
Re:FDA approves first systemic treatment for alopecia areata by the_only_law on Tuesday June 14, 2022 @06:08PM (#31746645)
I think it depends, bigger and stockier guys seem to pull it off pretty well.

I don't think I could pull it off though, at least right now. I have a taller, lankier statue and I worry I'd look like a skinhead.

I've seen some smaller guys pull it off as well, but they're usually shorter. Most guys that go clean shaven with my kinda build end up looking goofy.

On the flip side, long hair on bigger guys always looks odd to me.

Re:FDA approves first systemic treatment for alopecia areata by Grazester on Tuesday June 14, 2022 @10:02PM (#31748313)
13 years ago I started going to the gym because my hair started thinning. I was convinced a tall slim guy would look weird bald. I still have my hair albeit thinner than it was then but still there. I wonder if a life style change helped with that.
Re:FDA approves first systemic treatment for alopecia areata by rjh29 on Tuesday June 14, 2022 @08:24PM (#31747734)
Clean shaven and bald is definitely a difficult mix, probably a reason most people try to grow a beard. The hipster bald glasses beard look is cliched but preferable to your hair being half missing!
Re:FDA approves first systemic treatment for alopecia areata by halfnormalform on Tuesday June 14, 2022 @07:19PM (#31747205)
Kojak made baldness popular in the 70’s and 80’s: https://en.wikipedia.org/wiki/Telly_Savalas#Baldness_and_sta...
Re:FDA approves first systemic treatment for alopecia areata by amyjess on Tuesday June 14, 2022 @09:55PM (#31748274)
At the very least growing up as a kid in the '80s and early '90s, the only time I ever heard someone get compared to Kojak was as an insult. Shouting "Hey, Kojak!" at a bald guy was a good way to start a fight.
Re:FDA approves first systemic treatment for alopecia areata by nsxwolf on Tuesday June 14, 2022 @06:20PM (#31746748)
What ever happened to toupees? Young men seem to not even consider them as an option, even though the quality is better now than ever.
Re:FDA approves first systemic treatment for alopecia areata by failrate on Tuesday June 14, 2022 @06:24PM (#31746788)
You never notice the good toupees.
Re:FDA approves first systemic treatment for alopecia areata by threads2 on Tuesday June 14, 2022 @08:07PM (#31747615)
Be strong brothers. Turn to baldness.

"I'm proud of myself, for the way I accepted my baldness." - Larry David, the president of bald people.

https://youtu.be/Le4tih0tfbs?t=194

Re:FDA approves first systemic treatment for alopecia areata by pstuart on Tuesday June 14, 2022 @07:59PM (#31747557)
Finasteride seems like a miracle drug (cheap and effective) but unfortunately is not without risk for some users:

https://pubmed.ncbi.nlm.nih.gov/22789024/

Re:FDA approves first systemic treatment for alopecia areata by avan1 on Wednesday June 15, 2022 @12:35AM (#31749158)
i wish when people talk about Finasteride they always mention it that you won't be able to donnor blood after that. (FDA says you need at least 30 days Finasteride free for doing that)
Re:FDA approves first systemic treatment for alopecia areata by bamboozled on Tuesday June 14, 2022 @11:38PM (#31748855)
What about just accepting who you are and realizing that baldness is potentially even a blessing, less maintenance and if you're athletic, I think it's a good look, lots of women have complimented me on it since shaving my head and embracing it.
Re:FDA approves first systemic treatment for alopecia areata by LewisVerstappen on Tuesday June 14, 2022 @11:49PM (#31748917)
Umm yeah fuck that. I'd much rather pay $4 a month and keep my hair haha.
Re:FDA approves first systemic treatment for alopecia areata by koide on Wednesday June 15, 2022 @12:58AM (#31749278)
Is it more important than keeping your sexual function, though? https://pubmed.ncbi.nlm.nih.gov/22789024/
Re:FDA approves first systemic treatment for alopecia areata by LewisVerstappen on Wednesday June 15, 2022 @01:40AM (#31749495)
Sexual side effects are rare and I haven't experienced any. I also get regular blood work done so I can keep track of my metrics and my doctor will let me know if anything goes awry.

So yeah, not really concerned and will definitely keep taking Finasteride.

Re:FDA approves first systemic treatment for alopecia areata by koide on Wednesday June 15, 2022 @02:19AM (#31749714)
The point is that in all this thread, including in your previous comment, people are talking about it as if it had no possible side effects. So, great for you that you track your metrics and consult your doctor, but next time you stand behind a potentially devastating medicine, mention the downside and the care you take as well.
Re:FDA approves first systemic treatment for alopecia areata by redox99 on Wednesday June 15, 2022 @03:33AM (#31750122)
Some people simply look better with hair than without. If you have no side effects, and it's dirt cheap, why not just take a pill a day and be done with it?