I'm going to have to give this a try. I manage multiple Google Workspace accounts for clients and have stuck to Chrome for those as I have a profile set up for each account. Yes, you can log in to multiple Google accounts in any browser, but then it defaults to the first account for new windows.

The two final things that would get me off Chrome entirely:

* When I'm using my external USB microphone in a web-based conference system (mostly Cleanfeed but I've also seen it with Streamyard and Jitsi) my audio gets extremely robotic after a few minutes and it somehow impacts my entire system - I have to unplug the microphone to fix it.

* Dropbox, for some reason, hangs at 1 second left when uploading larger files (appx 60MB or so)

I've been looking for something like that. Thanks. But ideally, I don't want to swithswitch profiles. I want to have muliple instances of FF open, each with a different profile. Just like Chromium based browsers and users.

Anything for that?

When you choose a different profile in the Firefox Profile Switcher menu, it opens a new instance of Firefox with the new profile. The add-on experience will be very familiar if you've used Chromium's profile management features.

If you're trying to create a shortcut to Firefox that launches a profile other than the one you've selected as the default, the instructions for Linux and Windows are here:

https://kb.mozillazine.org/Shortcut_to_a_specific_profile

This is not necessary to use the profile feature, but some people prefer to launch profiles from shortcuts instead of a menu.

go to about:profiles in the omnibar and you'll be able to open multiple profiles from there. You can also do other general management of profiles.

This is how I use Firefox; you need Qubes OS for that.