Re:Fasting boosts stem cells’ regenerative capacity (2018)
by lm28469 on Tuesday May 17, 2022 @07:30AM
(#31408897)
Are you comparing fasting to breathing aluminium particles ?
Re:Fasting boosts stem cells’ regenerative capacity (2018)
by SemanticStrengh on Tuesday May 17, 2022 @07:48AM
(#31409062)
well I was not, only that between those two stressors, the same major biomarkers are involved. There often is a surprising level of similarities between seemingly distinct things and here I would bet there are possible comparisons however that is not the point of my parent comment, just an answer to which biomarkers are involved.
A more direct comparison would be with the acutes and long terms damages of hypoxia, because oxygen is a similar cofactor bottlenecking energy production, as is the absence of glucose/pyruvate from a fasting human which singlehandely rely of lipid/beta-oxidation.
e.g. https://pubmed.ncbi.nlm.nih.gov/21542052/
But it's not because those are the same mechanism (a bottleneck on a critical cofactor for ATP) that the effects have the same potency because of course fasting is less dangerous in strength than hypoxia.
for bioenergetics I don't remember the relevant ones although the manifestation is not only molecular, it can be observed (mitochondria respiration rate, uncoupling, etc) maybe this paper can show the relevant ones? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715336/