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A comment on Ingredient in Cough Syrup Could Work as an Antidepressant: Works Like Ketamine. Parent comment

Re:Ingredient in Cough Syrup Could Work as an Antidepressant... by raun1 on Wednesday May 04, 2022 @07:22PM (#31267154)
Like most dissociatives, it is unpleasant until it "clicks".

Once it clicks, it is just as pleasurable as Ketamine, Methoxetamine, and other related ACHs.

One major difference between DXM and K is that DXM is quite stimulating whereas K is rather subdued and relaxing. If you don't have dissociative experience besides Ketamine, I'm not surprised that trying DXM after K would lead to an unpleasant experience.

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Re:Ingredient in Cough Syrup Could Work as an Antidepressant... by dubswithus on Wednesday May 04, 2022 @09:23PM (#31268219)
I find ketamine to be a mix of stimulation and relaxation.

> Once it clicks, it is just as pleasurable as Ketamine, Methoxetamine, and other related ACHs.

If that was the case recreational users would move exclusively to research chemicals. There is a clear preference. But in some places DXM is much easier to access so that's what people do.

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