Re:Effects of fexofenadine, diphenhydramine, and alcohol on ...
by amluto on Saturday April 30, 2022 @04:27PM
(#31218989)
I would argue that, whatever “generation” it is, cetirizine does not deserve credit for being second generation. I know plenty of people with extremely obvious CNS effects from it. In contrast, loratadine seems innocuous.
[ Parent
| on HN ]
Re:Effects of fexofenadine, diphenhydramine, and alcohol on ...
by imdvayn on Saturday April 30, 2022 @04:37PM
(#31219089)
Unfortunately its justifiably classified as 2nd gen and IIRC studies show that it's generally more effective for hay fever. Personally, I've found that loratadine is pretty ineffective, especially after regular use.
Re:Effects of fexofenadine, diphenhydramine, and alcohol on ...
by jostmey on Saturday April 30, 2022 @04:39PM
(#31219101)
I found loratadine very effective but it takes time to work. At least a week
Re:Effects of fexofenadine, diphenhydramine, and alcohol on ...
by tyrfing on Saturday April 30, 2022 @05:00PM
(#31219304)
For me, loratadine was ineffective, and I can't distinguish cetirizine and fexofenadine - both are maybe 50-60% effective with no notable side effects, and allergy season means extra fatigue no matter what. Cetirizine does have the shortest half life.
Re:Effects of fexofenadine, diphenhydramine, and alcohol on ...
by isoprophlex on Saturday April 30, 2022 @04:32PM
(#31219027)
Second that, cetirizine definitely feels more like clemastine or meclizine than a proper second gen "non sedating" antihistamine. And with hay fever AND an allergy to nuts, I've tried them all, haha.