Re:Covid is becoming increasingly vaccine enabled
by jleyank on Sunday April 10, 2022 @09:17PM
(#30983484)
mRNA is only one of the various classes of vaccines that are approved for Covid. It's also been something that has been under development since SARS, and has been proposed as a drug-delivery mechanism for other diseases (think it's being tried for AIDS).
If one didn't want mRNA vaccines, there are others that older mechanisms for delivering inactivated viruses, protein fragments, etc.
EDIT: it's sorta a dream to have the patient manufacture the drug matter, particularly if it's manufactured in a particular site in the body. This could have applications in cancer treatments or for localizing side-effects. Something that only appears in the screwed-up environment of cancer cells beats the snot out of dosing something that happens to kill the cancer cells faster than the patient.
It was amazing. All testing was compressed from ~10 years to less than 1. For a brand new type of medical procedure using rna - that had previously failed to gain to approval. Hmm.
> effluent testing
I have heard about this sort of testing.. But again, since when did this become a thing? What does this sort of testing actually do, why is it something worth evaluating at all?
Edit to add my findings on effluent testing, from https://www.nature.com/articles/s41587-020-0690-1
"It is not currently possible to directly convert concentrations of viral RNA in wastewater to disease prevalence in a community. First, the biological variability in viral RNA excretion over time and between individuals creates problems in this estimate. This variability is then compounded by variability in the sewer systems across communities, particularly their size, configuration, and whether they include stormwater and industrial waste. However, longitudinal trends of SARS-CoV-2 RNA levels in wastewater can still be helpful in complementing traditional surveillance methods to understand trends in community transmission."