100% this is the best thing couples should do if they need therapy.
Anecdotally I see with my own relationship and that of couples I know that almost all problems are due to inadequate communication (Saying the wrong things / not saying the right things).
MDMA totally opens you up, enabling you do communicate this to your partner. "I really love you but sometimes I just wish you would X". Understanding the other person's emotional needs and how important they are will go a very long way in fixing a relationship.
What have you noticed since starting? I also have recently started treating ADD with this, and I'm starting to become much more in tune with my mind, and my emotional regulation issues are practically non-existent.
I'm on lisdexamfetamine and I don't have any side effect which is pretty crazy. Just calm, productivity and focus.
The enzyme, DDC, needed to make endogenous PEA needs adequate P5P to function.
https://www.uniprot.org/uniprot/P20711
https://pubmed.ncbi.nlm.nih.gov/1729407/
Decarboxylation of phenylalanine by aromatic L-amino acid decarboxylase (AADC) is the rate-limiting step in the synthesis of 2-phenylethylamine (PE), a putative modulator of dopamine transmission.
First, they share the same chemical structure as some of the neurotrasmitters that make us tick: dopamine, adrenaline and noradrenaline among others.
I have taken some of those mentioned in PIHKAL during my experimentation years, mostly MDMA and 2C-I and they taught me a lot about how my brain works and the power of psychedelics when used with care and responsibly. I can't wait for the day when science finds a way to leverage their capacity for deep introspection in psychotherapy and to manage mental pain. I know MDMA was previously used in couples therapy and and now in helping with PTSD.
Lastly, I've recently been diagnosed with ADHD and I'm trialling dexamphetamine, yet another phenethylamine, and it's been life changing the effect it's having on me.
Phenethylamines are pretty cool.