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Re:The Uselessness of Phenylephrine by astrange on Wednesday March 30, 2022 @04:23PM (#30860320)
Are you actually an MD?

I actually only ever hear about acetaminophen/paracetamol being dangerous from Americans - in other Anglo countries everyone will happily suggest you take it all the time, it is available OTC, and it comes as something kids will mistake for lemonade.

https://www.amazon.co.uk/Lemsip-Cold-Blackcurrant-Flavour-Sa...

> Ibuprofen and Aspirin are not perfect but they are much, much, much safer than tylenol is.

Only short term. Ibuprofen is less safe taken chronically, it'll destroy your stomach lining.

Re:The Uselessness of Phenylephrine by cortesoft on Wednesday March 30, 2022 @04:56PM (#30860669)
> For the average healthy adult, the generally recommended maximum daily dose is no more than 4,000 milligrams (mg) from all sources. But in some people, doses close to the 4,000 mg daily limit for adults could still be toxic to the liver.

https://www.health.harvard.edu/pain/acetaminophen-safety-be-...

4,000 mgs is easy to hit for people who don't realize that it can be dangerous. I know lots of people who would say "Well, my pain is bad, let me take double"... which for extra strength would be 4 x 500 MG, which is 2000 MGs in a single dose... which then if you do it twice in a day is right there at the 4000 MG mark. Most people are fine with that, but some people can get really sick.

If the person then does it 3 times a day, they are close to the danger zone for most people and over the danger zone for some people. Then multiply that by a few days....

You can easily say, "Well, they are taking more than they are supposed to!", but it is really common to take a bit extra if you feel really bad without realizing how dangerous it is, because Tylenol is `safe`

Re:The Uselessness of Phenylephrine by paulmd on Wednesday March 30, 2022 @04:40PM (#30860510)
No, I am not. It's a dune reference.

Ulcers ("destroying your stomach lining") is less bad than "destroying your liver", and typically you will have to screw up harder before other NSAIDs reach that level. Tylenol literally is dangerous following the directions on the bottle, because those directions aren't calibrated for chronic usage, when they say "daily max" they don't mean you take it daily, that dose is even lower.

Re:The Uselessness of Phenylephrine by rscho on Wednesday March 30, 2022 @04:51PM (#30860619)
This is wrong. Kidney failure from NSAIDs is very common, and also very dangerous. And can develop at recommended dosage.
Re:The Uselessness of Phenylephrine by paulmd on Friday April 01, 2022 @03:24AM (#30875953)
hey, thanks for the correction from a real doctor, I will be much more perceptive of that risk in the future.

again, I don't do analgesics daily but I will be sure to adhere to the doage schedule on that. Pain medication is such an unfortunate area of medicine.

Re:The Uselessness of Phenylephrine by astrange on Wednesday March 30, 2022 @05:04PM (#30860744)
I had a roommate who nearly died (his words) from taking a chronic regular dose of ibuprofen for a month or two when he was sofa-ridden after tearing his ACL.