You don't need anything to build a node.js app. If you use typescript then yes you'll want typescript, but honestly the experience out of the box in node is pretty fantastic that you don't need anything else, as far as build goes.

Granted if you are talking frontend browser code then sure webpack, but that tool has been around and stable for many years now.

Added bonus too is browser adoption is way better than ever so you don't really need a transpile either, typescript being the exception.