News for hackers. Stuff that matters.

A comment on Ivermectin Didn’t Reduce Covid-19 Hospitalizations in Largest Trial to Date.

Re:Ivermectin Didn’t Reduce Covid-19 Hospitalizations in Lar... by cersa8 on Friday March 18, 2022 @08:42AM (#30721426)
Isn't Ivermectin most effective at the onset of symptoms [0] ? From the article "They looked at data from all patients; then analyzed data from patients who received ivermectin or a placebo 24 hours before they were hospitalized" This sounds like Ivermectin was given when symptoms where so severe, hospitalization was required. This could well be too late for Ivermectin to be effective.

[0] https://www.ijidonline.com/article/S1201-9712(20)32506-6/ful...

[ Parent | on HN ]
Re:Ivermectin Didn’t Reduce Covid-19 Hospitalizations in Lar... by acdha on Friday March 18, 2022 @09:32AM (#30721993)
No. Ivermectin has not proven effective at any point.
[ Parent | on HN ]
Re:Ivermectin Didn’t Reduce Covid-19 Hospitalizations in Lar... by liquid_bluing on Friday March 18, 2022 @05:20PM (#30727677)
Has it been proven not effective at all points?
[ Parent | on HN ]
[dead]
Re:Ivermectin Didn’t Reduce Covid-19 Hospitalizations in Lar... by acdha on Friday March 18, 2022 @09:50AM (#30722204)
No, it hasn’t. You’re linking to a famously anonymous site which doesn’t control for quality because the purpose is to give people a number which looks positive secure in the knowledge that very few readers will notice how the studies showing positive effects are flawed or limited.
[ Parent | on HN ]
Re:Ivermectin Didn’t Reduce Covid-19 Hospitalizations in Lar... by pjkundert on Friday March 18, 2022 @11:15AM (#30723340)
There are those who claim that you can accurately predict project timelines from the top down -- high-quality estimates, so to speak.

However, this doesn't work. Talk to anyone in software for any significant duration.

You make accurate high-level estimates, using a multitude of small, low-quality estimates.

I trust many independent peer-reviewed studies (102) plus a large number of other studies (another 49), whose outcomes are consistent with all other studies (efficacy declines linearly from 0-7 days after onset). I do not trust a single, large study focussed after the efficacy window has expired.

The big question is -- why would you trust such a study, if you surveyed and understood the efficacy decline consistent with all other studies?

[ Parent | on HN ]