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Re:Ivermectin Didn’t Reduce Covid-19 Hospitalizations in Lar... by pjkundert on Friday March 18, 2022 @11:15AM (#30723340)
There are those who claim that you can accurately predict project timelines from the top down -- high-quality estimates, so to speak.

However, this doesn't work. Talk to anyone in software for any significant duration.

You make accurate high-level estimates, using a multitude of small, low-quality estimates.

I trust many independent peer-reviewed studies (102) plus a large number of other studies (another 49), whose outcomes are consistent with all other studies (efficacy declines linearly from 0-7 days after onset). I do not trust a single, large study focussed after the efficacy window has expired.

The big question is -- why would you trust such a study, if you surveyed and understood the efficacy decline consistent with all other studies?

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