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A comment on Saffron and major depressive disorder: meta-analysis of clinical trials (2013). Parent comment

Re:Saffron and major depressive disorder: meta-analysis of c... by eurasiantiger on Monday March 14, 2022 @07:47AM (#30671256)
Depends on how much of it is required for antidepressant effect. It may not be that much.

Saffron definitely has psychotropic effects, there are anecdotal reports of mild MDMA-like effects when used sublingually in a satchel.

Not that surprising because safrole is an MDMA precursor.

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Re:Saffron and major depressive disorder: meta-analysis of c... by giantg2 on Monday March 14, 2022 @08:43AM (#30671710)
True. At 100mg per day (from one of the studies) it would be about $250 per year (at spice prices, no idea what pharma will mark it up as).
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