News for hackers. Stuff that matters.

A comment on Saffron and major depressive disorder: meta-analysis of clinical trials (2013).

Re:Saffron and major depressive disorder: meta-analysis of c... by mckirk on Monday March 14, 2022 @07:24AM (#30671049)
For information on supplements like this, examine.com[1] is great. For many things, there is a "Human Effect Matrix" on there, which gives a good overview of the effects that were observed in studies, their magnitude, and how consistently they were found. For saffron for example, the evidence that it can help against depression is fairly solid, as other studies have shown as well[2].

Sadly, a lot of information on Examine is hidden behind a paywall by now, but it's still a really valuable resource.

[1]: https://examine.com/supplements/saffron/#effect-matrix [2]: https://pubmed.ncbi.nlm.nih.gov/31669837/

[ Parent | on HN ]
Re:Saffron and major depressive disorder: meta-analysis of c... by radu_floricica on Monday March 14, 2022 @07:34AM (#30671137)
Examine membership is WELL worth it. The first page of the human effect matrix: https://prnt.sc/MSN54mFgUAP0

The combination of "notable effects" and "very high consistency" is pretty rare among supplements. I should eat more saffron...

[ Parent | on HN ]
Re:Saffron and major depressive disorder: meta-analysis of c... by giantg2 on Monday March 14, 2022 @07:28AM (#30671082)
In case others were wondering, Examine requires a membership for the human effect matrix.
[ Parent | on HN ]
Re:Saffron and major depressive disorder: meta-analysis of c... by mckirk on Monday March 14, 2022 @07:41AM (#30671216)
That's strange, I don't have a membership and can see "Human Effect Matrices" for individual supplements without a problem. Only the inverse search, i.e. the matrix for "what helps against depression" is limited to three supplements for me.
[ Parent | on HN ]
Re:Saffron and major depressive disorder: meta-analysis of c... by giantg2 on Monday March 14, 2022 @08:45AM (#30671725)
You're right. It gives me some stuff, but says to see the full details I would need a membership.
[ Parent | on HN ]