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Re:Woman appears cured of HIV after umbilical-cord blood tra... by mmastrac on Tuesday February 15, 2022 @01:55PM (#30350996)
Totally tangential, but this was a shocking sentence from that post...

> plancentas are so valuable that physicians - especially in Europe - sometimes prefer to take them for themselves to sell to cosmetics research for ~$50k

I wonder if there's a hybrid approach where you could share the placenta/umbilical cord w/other companies and get free storage.

Re:Woman appears cured of HIV after umbilical-cord blood tra... by Alex3917 on Tuesday February 15, 2022 @02:28PM (#30351410)
You can donate cord blood for free to a public bank. Obviously you're not guaranteed that it won't be used by someone else before a sibling potentially needs it, but the chances of it being useful to your own family are almost zero anyway -- not exactly zero, but if you were making a list of the ways to best increase your life expectancy given $5k to spend, I doubt it would even make the top 1,000 options in terms of expected ROI.
Re:Woman appears cured of HIV after umbilical-cord blood tra... by pkukp9 on Tuesday February 15, 2022 @05:57PM (#30354056)
hello - founder of Anja Health here :)

I would actually argue that the chances of using it are actually much higher & it would make the top 1000 options in terms of expected ROI. Using type 1 diabetes as an example:

By age 18, approximately 1/300 people in the US develop type 1 diabetes

https://www.medicalnewstoday.com/articles/240160#1 -> here's an article demonstrating how cord blood has successfully reversed type 1 diabetes

and that's just for diabetes. Consider the chances and corresponding research around cerebral palsy, hair loss, heart failure, liver disease, cancers, and more that stem cells - and specifically cord blood stem cells - have been successfully used for.

Re:Woman appears cured of HIV after umbilical-cord blood tra... by metb on Wednesday February 16, 2022 @07:52AM (#30359366)
There was some research that indicated stem cells can be made from skin cells. Is there a chance this field will eventually catch up by the time stem cell therapies become more widely accesssible?
Re:Woman appears cured of HIV after umbilical-cord blood tra... by pkukp9 on Wednesday February 16, 2022 @11:52AM (#30362337)
Those stem cells are more unstable than cord blood stem cells. Right now they can be carcinogenic!
Re:Woman appears cured of HIV after umbilical-cord blood tra... by metb on Thursday February 17, 2022 @02:40AM (#30370495)
Thanks for replying. Would like to learn more about the carcinogenic aspect of these stem cells. Can you share any pointers.
Re:Woman appears cured of HIV after umbilical-cord blood tra... by acchow on Tuesday February 15, 2022 @02:37PM (#30351527)
What would be some things you might expect to see in the top 50?
Re:Woman appears cured of HIV after umbilical-cord blood tra... by op00to on Tuesday February 15, 2022 @02:57PM (#30351795)
- Spend good money on therapy - At home exercise equipment - Dental care

Just a few things off the top of my head.

Re:Woman appears cured of HIV after umbilical-cord blood tra... by Alex3917 on Tuesday February 15, 2022 @02:52PM (#30351737)
Things generally related to diet, exercise, health, and education.
Re:Woman appears cured of HIV after umbilical-cord blood tra... by acchow on Tuesday February 15, 2022 @07:06PM (#30354717)
I don't think of "exercise" as a "5k" investment. Sure you could buy 5k worth of equipment, but how much more does that improve your health over calisthenics and a set of dumbbells?

Yes, education I'd say is in the top 10 or 50. But how can you possibly fill out the top 1000 without including umbilical cord stem cells?

Re:Woman appears cured of HIV after umbilical-cord blood tra... by jacquesm on Tuesday February 15, 2022 @03:24PM (#30352126)
That claim is bullshit, see my comment in that thread.
Re:Woman appears cured of HIV after umbilical-cord blood tra... by tptacek on Tuesday February 15, 2022 @07:27PM (#30354871)
I don't know if you're just having a bad day or something but the comment you're referring to is pretty aggro.
Re:Woman appears cured of HIV after umbilical-cord blood tra... by jacquesm on Tuesday February 15, 2022 @07:32PM (#30354904)
Yes, I take issue with people accusing doctors of crimes on the basis of hearsay, especially to promote their own products.
Re:Woman appears cured of HIV after umbilical-cord blood tra... by sooheon on Wednesday February 16, 2022 @03:18AM (#30357527)
I found at least one article:

NHS hospital sells placentas for cosmetic use

https://web.archive.org/web/20210217162113/https://www.teleg...

Not 50k a pop, but shows that it does happen.

Re:Woman appears cured of HIV after umbilical-cord blood tra... by jacquesm on Wednesday February 16, 2022 @03:35AM (#30357612)
> I found at least one article:

No, you found one article.

> Not 50k a pop, but shows that it does happen.

It shows it did happen, 13 years ago.

Compare with the claims made by Anjahealth's CEO.

(1) an 'NHS hospital in the UK' is not 'doctors in the EU', (2) it is universally condemned, (3) the beneficiary is apparently a US company (4) Consent was obtained but for different reasons (medical research), which put the hospital in hot water, as it should. (5) the amount is nowhere near the one claimed. (6) it is a donation, clearly still a quid-pro-quo. (7) this is outrageous enough that it made the newspaper. (8) 2008.

To use this in a commercial setting, to pretend it's an ongoing and common thing and that doctors in the EU profit from this is absolutely disgusting. Besides that I sincerely hope that that hospital had the book thrown at it, and suspect the company is at fault and not the hospital.

Accusations like that against doctors should not be made lightly, especially not for your own personal financial gain.

Finally: placentas are used for good research, they are a rich source of stem cells and hard to come by proteins, some hospitals do collect them for this purpose (as the hospital in the article pretended to do), and by making the argument that they are mostly used for cosmetics manufacture it harms the main reason hospitals will pass them on: to help with various medical research programs, which the company is essentially in competition with.

It's a straight up case of FUD with unsupported accusations of insane profits on unethical behavior against a group of people that have taken a pretty expensive oath as well as operating under strict regulations.

edit: some more research later:

It appears the hospital was unaware of what the company did:

" She added: "We have spoken to Sigma-Aldrich already and asked them to revise the consent form so it is more explicit. We partook in the scheme on the understanding that the placentas would be used for medical research."

She added mothers were given information about the process during ante-natal care and placentas were only ever taken with their consent.

She added: "We do receive a donation for this service, but we are not paid for it as such. The distinction is that even if we didn't receive a donation, we would still offer mothers the opportunity to donate their placentas for research, rather than have them incinerated."

Sigma-Aldrich, which has a facility in Fancy Road, Poole, denied its human placental by-products are used in the manufacture of any cosmetic products, but a spokesman admitted they may be used in their development and testing. "

https://www.bournemouthecho.co.uk/news/2279703.placenta-ange...

Based on the information available the hospital made yet another questionable call here, revising the consent form isn't the solution, the solution is to stop working with this company because it clearly can't be trusted.

Re:Woman appears cured of HIV after umbilical-cord blood tra... by sooheon on Monday February 21, 2022 @06:21AM (#30414487)
Hospitals seem to routinely deny mothers the right to take their placenta with them: https://www.vice.com/en/article/xd57m3/heres-why-women-are-s...

> Dr. Kristal pointed out, with slight hesitancy, that research hospitals could have a financial motive to keeping women's placentas given that "a lot of bigger hospitals have—or, at least, had—contracts with pharmaceutical and cosmetic houses to sell the placentas." The hospitals I spoke with denied this allegation, but it's perhaps worth noting that Baylor Hospitals—which is notorious for refusing to let moms take home their placentas—is also part of a national study to evaluate the efficacy of using cells derived from human placenta to treat Crohn's disease.

Or another report:

https://www.medpagetoday.com/special-reports/exclusives/8273...

> One of the most widely used products for lower extremity wounds, Lantis said, is EpiFix, which is made by MiMedx. It is synthesized from "dehydrated human amnion/chorion membrane" -- placental material -- according to the company's website. In 2013, the FDA warned the company about marketing the product without approval, which the firm eventually obtained.

> If women knew more about the money, power, and scandal behind their donations, they might see donation differently, Turner said.

> "What if women were given the full account, that some biobank is going to acquire it, process it, assign it value, and then it's going to be marked up and sold again," Turner said. "Some women might think twice."

These are just in the first page of google results. It's shady but not exactly illegal (apparently) to ask mothers on the operating table to sign off on "donating" their placentas.

If such donations are regularly solicited, I don't find it that surprising that hospitals profit off of them one way or another. I do agree the CEO should back up her claims.

Re:Woman appears cured of HIV after umbilical-cord blood tra... by pkukp9 on Tuesday February 15, 2022 @05:59PM (#30354073)
A doula told me that she saw this happen in the US once too. It's not legal, but I think there are legal loopholes around it. Another OBGYN told me it's more common in Europe
Re:Woman appears cured of HIV after umbilical-cord blood tra... by skrbjc on Tuesday February 15, 2022 @03:10PM (#30351959)
That should be illegal
Re:Woman appears cured of HIV after umbilical-cord blood tra... by jacquesm on Tuesday February 15, 2022 @04:15PM (#30352815)
It is.