Consider if your first impulse is to deny the possibility of that last point. You’re probably not an evolutionary virologist, so the truth is you have no idea which mutations are next. Perhaps you think T-cell immunity will save you, but omicron already escapes >50% of T-cell antibody types in 21% of vaccinated or infected people. Will we develop better cross-neutralizing antibodies from omicron or will antigen imprinting doom us to suffering wave after wave of new variants, due to maintaining variant-specific immunity only?
I bet that feeling of self-righteousness is satisfying, isn’t it? Perhaps that’s because blaming other humans subconsciously lets you continue the illusion that humans were ever in control of the pandemic in the first place or that a real risk ever existed for you. Anger is a lot more comfortable than existential anxiety.
But the truth is, it’s not “the man” who’s keeping you down at all — the pandemic limitations you feel right now are the libertarian equivalent to your fist being restrained from meeting your neighbor’s nose.
https://www.healthcare.gov/how-plans-set-your-premiums/
Cellular immunity is highly durable and effective.
The question is not how long the immunity lasts (based on original SARS patients, probably multiple decades to a lifetime), but whether affinity-matured T-cells can sufficiently cover the antigen-space of future ACE2-binding spike proteins.
Somatic hypermutation might still be too complex to model computationally to answer that question outright.
Do you know whether this question is answerable in another way?
Like fuck I’m gonna keep getting boosters but still need to show papers and wear masks. I’m not a sucker.