Personally, it used to be the biggest issues in tackling scripting tasks in Lisp in my experience was slow startup (mind you, we're talking about running from 4200 rpm spinning rust). There are people successfully using it for such kind of work, and generally it used to be common in environments with more Lisp support.

These days my biggest issue is that I kind of lost the need for anything more than Bash for one-off tools, and I do it rarely enough that the incremental benefit faces big hurdle of dealing with development-antagonistic environment (mac)