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Re:Moderna’s HIV vaccine has officially begun human trials by ImaCake on Tuesday February 01, 2022 @05:41PM (#30170610)
The lipid vesicles part is pretty simple I think. You don’t need it to last a long time, just long enough to snort it up your nose.

I am not sure about the XNAs. You might be able to get around it with increasing the dose (trivial if you are producing your own RNA) or it might be possible to use XNAs in a standard synthesis protocol. It would depend on the RNA Pol I think.

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