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A comment on Moderna’s HIV vaccine has officially begun human trials. Parent comment

Re:Moderna’s HIV vaccine has officially begun human trials by dnautics on Monday January 31, 2022 @04:20PM (#30154568)
> "these are not the antibodies most humans develop in response to HIV."

In many cases. One case, for example was identified from a prostitute in sub-saharan africa who managed to be completely HIV-free. It turned out she had a mutation in her antibodies that caused the antibodies to latch onto things with four sites instead of just 2 (think X shaped instead of V shaped).

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Re:Moderna’s HIV vaccine has officially begun human trials by mlyle on Monday January 31, 2022 @07:14PM (#30156823)
That's why I said "most humans". bnAbs are generally antibodies that are detected in (few) humans. In addition to the people with seeming immunity through missing receptors or unusual antibody morphology, there's also about 1 in 200 infected that are "elite controllers" that do not develop high viral loads or severe symptoms when infected by HIV-- generally in large part to their bodies making multiple bnAbs.
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Re:Moderna’s HIV vaccine has officially begun human trials by dnautics on Tuesday February 01, 2022 @12:36AM (#30158993)
I wasn't contradicting you, I was adding more specifics.
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Re:Moderna’s HIV vaccine has officially begun human trials by andrewflnr on Monday January 31, 2022 @05:08PM (#30155290)
That sounds fascinating. Got any links or search terms?
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Re:Moderna’s HIV vaccine has officially begun human trials by dnautics on Monday January 31, 2022 @05:13PM (#30155378)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136306/
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Re:Moderna’s HIV vaccine has officially begun human trials by andrewflnr on Monday January 31, 2022 @09:56PM (#30158075)
Awesome.
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