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A comment on Moderna’s HIV vaccine has officially begun human trials. Parent comment

Re:Moderna’s HIV vaccine has officially begun human trials by im3w1l on Monday January 31, 2022 @01:52PM (#30152360)
The slow part is the safety testing right? If we had a robust enough theory of vaccines safety we could reduce that. How are the yearly flu shots tested anyway? Now, I would not take such a HIV shot. But for high risk groups, think promiscious homosexuals, it may eventually be worth it.
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Re:Moderna’s HIV vaccine has officially begun human trials by f6v on Monday January 31, 2022 @02:05PM (#30152578)
If we had robust enough theory of vaccine testing it wouldn’t matter what kind of vaccine you develop, right?
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Re:Moderna’s HIV vaccine has officially begun human trials by lobocinza on Wednesday February 02, 2022 @10:06PM (#30188018)
I'm not from a bio-science area but AFAIK mRNA vaccines are robust.

1. The same mechanism of deliver is used so it's already tested and know to be safe/effective.

2. It replicates the same protein(s) found on the virus. So it will not due more damage than getting the virus and it will have a high probability of being effective.

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Re:Moderna’s HIV vaccine has officially begun human trials by im3w1l on Monday January 31, 2022 @02:12PM (#30152671)
Maybe, maybe not? Mrna vaccines are very customizable so they could be specifically engineered to avoid known safety issues for example.
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Re:Moderna’s HIV vaccine has officially begun human trials by rzz3 on Monday January 31, 2022 @10:29PM (#30158295)
If we can do it this fast and this safely for COVID, we should do the same for this disease.
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Re:Moderna’s HIV vaccine has officially begun human trials by grayfaced on Monday January 31, 2022 @11:43PM (#30158705)
Efficacy trials are quick for a disease with 100k infections a day. It's much slower for something that has that many cases a year. It's much harder to tell a statistical difference from noise when you're talking minuscule cases in trial groups.
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Re:Moderna’s HIV vaccine has officially begun human trials by dragonwriter on Tuesday February 01, 2022 @02:10AM (#30159507)
> The slow part is the safety testing right?

No, the slow part is the efficacy testing.

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