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Re:Moderna’s HIV vaccine has officially begun human trials by helloworld on Monday January 31, 2022 @01:20PM (#30151807)
"Prof. William Schief explains how the novel #HIV #vaccine being tested in human clinical trials can trigger the right #Bcells of the immune system to achieve the much sought after broadly neutralizing #antibodies."

https://twitter.com/scrippsresearch/status/13581208549709127...

Re:Moderna’s HIV vaccine has officially begun human trials by dmix on Monday January 31, 2022 @01:37PM (#30152083)
Direct link to video: https://www.youtube.com/watch?v=BrmXpMmvHWw

This explains the background on broadly neutralizing antibodies that the other commenter `mlyle` mentions. Worth the watch.