The impact that AlphaFold is already having on speeding up drug discovery

Posted by alphabetting on Sunday January 23, 2022 @11:43AM
from the twitter.com dept.

https://twitter.com/russelljkaplan/status/1485191271840837633

( 4 comments | 10 points | on HN )

Re:The impact that AlphaFold is already having on speeding u... by samaman on Sunday January 23, 2022 @04:08PM (#30050457)

I'd be very very worried about a protein model that just came out alphafold to be used to come up with drug targets without at least some molecular dynamics simulation of the solution within which that protein works with. There may be other glycans, ligands, or wholly different metabollites that could affect this binding.

[ Parent | on HN ]

Re:The impact that AlphaFold is already having on speeding u... by was_a_dev on Sunday January 23, 2022 @12:04PM (#30047819)

What is the licensing of AlphaFold? If the drug makes it to market, does the creators owe royalties?

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Re:The impact that AlphaFold is already having on speeding u... by eesmith on Sunday January 23, 2022 @01:00PM (#30048484)

One of the follow-ups points to https://github.com/deepmind/alphafold/issues/14#issuecomment... which comments "Hi, we have recently changed the license terms for the AlphaFold weights to CC BY 4.0, which permits commercial use", from 4 days ago.

It looks like the source license at https://github.com/deepmind/alphafold/blob/main/LICENSE is Apache 2.0.

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Re:The impact that AlphaFold is already having on speeding u... by was_a_dev on Sunday January 23, 2022 @01:57PM (#30049159)

Sounds like that startup was hedging their bets for the license to change

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