Those who'd had Covid-19 less likely than vaxxed to be infected in Delta wave

Re:Those who'd had Covid-19 less likely than vaxxed to be in... by thehappypm on Wednesday January 19, 2022 @09:51PM (#30003841)

I wonder if an ideal vaccine would mimic natural infection. A natural infection grows and grows and grows until the immune system finally gets going and snuffs if out, over the course of days or weeks.

Perhaps a slow-release vaccine would work better than a multi dose regimen? Two or three huge doses doesn’t really mimic anything like what an infection actually looks like.

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Re:Those who'd had Covid-19 less likely than vaxxed to be in... by benpiper on Saturday January 22, 2022 @11:04PM (#30043539)

There's always a balancing act between vaccine safety and efficacy. The smallpox vaccine mimics a natural infection, but it's extremely dangerous because people who get vaccinated can actually spread real smallpox to others for a period of time, so they have to stay isolated.

Pre-Covid coronavirus vaccines tested in animals induced antibody-dependent enhancement and were thus deemed unsafe for human trials. A safe, effective Covid vaccine was always a long shot. Maybe one day we'll get one, but maybe we won't. Thankfully, there are multiple other drugs that are effective at preventing and treating Covid.

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Re:Those who'd had Covid-19 less likely than vaxxed to be in... by ttfkam on Wednesday January 19, 2022 @10:29PM (#30004164)

> A natural infection grows and grows and grows until the immune system finally gets going and snuffs if out, over the course of days or weeks.

Or you grow progressively weaker, miserable, and slowly suffocate until your body gives out—all without your family at your side.

(There's a reason we do not strive for even approximate mimicry of actual disease if we can help it.)

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