Mirtazapine can help with depression, anxiety and panic, and it isn't an SSRI. There are also newer drugs that are marketed as SMS drugs instead of SSRIs, like vilazodone and vortioxetine. Buspirone binds to 5HT1A directly, instead of inhibiting the serotonin transporter like other drugs.

Wellbutrin and NDRIs typically aren't that great for anxiety, but they can help.