That doesn't seem obvious to me. I'd be more inclined to think anyone willing to pay to avoid ads likely isn't very receptive to advertising in the first place. If someone is so annoyed by ads, they're probably not going to be clicking on them, right?

In terms of purchasing power they might look desirable, but surely they’re also likely to be massively overrepresented as users of ad blocking solutions (also pure speculation on my part). That could make them less profitable in practice.