To get nice integer scaling one could render at 15360x8640 (16k) which is 5x3072x1728 and 4x3840x2160 but I doubt that's what Wayland is doing. No common graphics card could handle that.
The font hinting relies on the resolution too. By scaling the rendered pixmap 125% the fonts would look bad too. Rendering the fonts in a larger size at the native screen resolution should look better.
https://discourse.gnome.org/t/how-fractional-scaling-works-i...
For scaling 125%, the client windows are rendered at 2x their size and sampled down. On the parent's system, a full-screen window would be rendered at 6144x3456 and scaled down to 3840x2160 (0.625%).
This gives a blurry result and is taxing on the graphics chip.
Qt apps and Firefox support scaling themselves which gives a much crisper result for fonts and line-art.
But a 1080p screen would be a no for me. At 2256x1504 on 13.5" screen I think Framework laptop would probably be fine at 100% ie no scaling