Sure. I did not mean to imply that SEH itsef requires the C runtime. However, the __CxxFrameHandler3 that Rust/llvm uses would need to be rewritten.
IIRC llvm itself generates calls to __CxxFrameHandler3 when SEH is being used, making it awkward to replace with something that's not compatible.
https://docs.microsoft.com/en-us/windows/win32/debug/vectore...
Granted, they are more cumbersome to use and probably not worth the effort to try to avoid them other than special cases.