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Re:Stanford requires booster shots for all students by disgruntledphd2 on Thursday December 30, 2021 @01:47PM (#29739882)
I too desperately want a sterilizing vaccine. Given the existence of influenza and the common cold (a bunch of rhino and corona viruses), this seems unlikely unfortunately.
Re:Stanford requires booster shots for all students by eli_gottlieb on Thursday December 30, 2021 @01:53PM (#29739951)
If it seems unlikely, then someone should explain why it works in a mouse model but not in the real world. If the virus mutates too quickly for a full sterilizing vaccine, then nonetheless, any vaccine that reduces transmission is helpful. If the virus mutates too quickly period, all the more reason for variant-specific boosters, targeted to the strains circulating, just like the yearly flu shot.
Re:Stanford requires booster shots for all students by bigbillheck on Thursday December 30, 2021 @02:17PM (#29740271)
> someone should explain why it works in a mouse model but not in the real world.

As the saying goes, 'mice lie and monkeys exaggerate'.

Re:Stanford requires booster shots for all students by disgruntledphd2 on Thursday December 30, 2021 @02:49PM (#29740668)
The current vaccines do, in fact, reduce transmission. This efficacy drops over time, but it definitely exists.