Re:Stanford requires booster shots for all students
by disgruntledphd2 on Thursday December 30, 2021 @01:47PM
(#29739882)
I too desperately want a sterilizing vaccine. Given the existence of influenza and the common cold (a bunch of rhino and corona viruses), this seems unlikely unfortunately.
Re:Stanford requires booster shots for all students
by eli_gottlieb on Thursday December 30, 2021 @01:53PM
(#29739951)
If it seems unlikely, then someone should explain why it works in a mouse model but not in the real world. If the virus mutates too quickly for a full sterilizing vaccine, then nonetheless, any vaccine that reduces transmission is helpful. If the virus mutates too quickly period, all the more reason for variant-specific boosters, targeted to the strains circulating, just like the yearly flu shot.
Re:Stanford requires booster shots for all students
by bigbillheck on Thursday December 30, 2021 @02:17PM
(#29740271)
> someone should explain why it works in a mouse model but not in the real world.
As the saying goes, 'mice lie and monkeys exaggerate'.
Re:Stanford requires booster shots for all students
by disgruntledphd2 on Thursday December 30, 2021 @02:49PM
(#29740668)
The current vaccines do, in fact, reduce transmission. This efficacy drops over time, but it definitely exists.
And whatever happened to the project of vaccines that provide full, sterilizing immunity? Last publication I can find is for a study in freaking mice[1]. Is there no imperative to actually provide sterilizing immunity at "warp speed", because society can just shove non-sterilizing vaccines into people and save on ICU beds?
[1] -- https://www.cell.com/iscience/fulltext/S2589-0042(21)01005-1