You can't really ad-block from astroturfed ads, for example a 'viral' video of Amazon delivery driver dancing on a Amazon Ring doorbell get to the top of a video subreddit. That can't be blocked against.

I run agressive ad blocks and I'll still get pictures on r/aww/ of a kitten next to a freshely delivery KFC - with a title like "Kittens first every KFC delivery to investigate".

What I'd like to know is how Reddit monetizes those ads that make it through to everyone.