Re:More than half of high-impact cancer lab studies could no...
by tsbischof on Friday December 10, 2021 @03:05AM
(#29507567)
It is worse than nothing, because incorrect positive results and non-published negative results lead people to waste years of their lives building off something which is not true.
Re:More than half of high-impact cancer lab studies could no...
by ajsnigrutin on Friday December 10, 2021 @03:24AM
(#29507679)
Yep, and "nothing" (as in "the effect of X on Y is zero") is a meaningful result, possibly a very important one, but being "nothing", it has a lot lower chance of actually getting published.
Re:More than half of high-impact cancer lab studies could no...
by Retric on Friday December 10, 2021 @06:00AM
(#29508534)
The issue is “nothing” is not sufficient to assume zero effect, it just means the effect wasn’t measured. Actual progress means trying to replicate both positive and negative results.
Re:More than half of high-impact cancer lab studies could no...
by ajsnigrutin on Saturday December 11, 2021 @03:37AM
(#29519477)
Well yeah, but if you're trying to "cure cancer", and in a (just made-up) theory an acidic environment should help with cancer, so you try lemon juice, and it shows that lemon juice cures as much cancer as placebo does, that seems publishable to me.
This looks like such a fundamental problem to me. Zooming out, studies are explorative into the unknown, outside of our knowledge. We should expect most of them to find nothing.