I mentioned downthread about a project called Styletron, which has styled-components-like devexp, but compiles to atomic CSS for the bundle size benefits.

Another variation I've seen is a combination of atomic CSS and Mithril.js' hyperscript selector syntax, which lets you do stuff like this:

    const Button = 'button.bg-gray-900.px-6.text-white';

    // JSX
    return <Button>Click me</Button>

There definitely are interesting ways of applying atomic CSS beyond basic Tailwind usage.