Re:The Impact of Vitamin D Level on Covid-19: Systematic Rev...
by bronto on Friday November 26, 2021 @07:23PM
(#29355808)
I agree. Take a zinc copper combination. Taking one will lower the other and vice versa.
Re:The Impact of Vitamin D Level on Covid-19: Systematic Rev...
by podgaj on Saturday November 27, 2021 @07:40AM
(#29359719)
Just a correction, Zinc only lowers copper, copper does not lower zinc. Zinc creates metallothioneins that stops copper from being absorbed into circulation from the intestine.
https://onlinelibrary.wiley.com/cms/asset/209a432f-1eb4-4c01...
So why is this a surprise? Why do you think we need these vitamins and hormones? (Vitamin D is actually a hormone) For our health! You will find that many of the risk factors of COVID are also outcomes of vitamin D deficiency.
https://portlandpress.com/biochemj/article-abstract/474/8/13... https://clinicalhypertension.biomedcentral.com/articles/10.1...
But what should be being studied even more than Vitamin D?
ZINC.
A zinc deficiency not only effects ACE and ACE2, but also ADAM17, which cleaves ACE2 off the cell to make soluble ACE2. When the virus attaches to soluble ACE2 it cannot enter the cell.
https://www.mdpi.com/viruses/viruses-12-00491/article_deploy...
More studies on Soluble ACE2 and COVID that are constantly ignored:
A novel soluble ACE2 protein protects from lethal SARS-CoV-2 infection https://pesquisa.bvsalud.org/global-literature-on-novel-coro...
Bioengineered angiotensin-converting-enzyme-2: a potential therapeutic option against SARS-CoV-2 infection https://www.nature.com/articles/s41371-021-00636-y
Tumor Necrosis Factor-α Convertase (ADAM17) Mediates Regulated Ectodomain Shedding of the Severe-acute Respiratory Syndrome-Coronavirus (SARS-CoV) Receptor, Angiotensin-converting Enzyme-2 (ACE2) https://www.sciencedirect.com/science/article/pii/S002192582...
AKI in a mouse model of COVID-19: Therapeutic potential of a novel soluble ACE2 variant https://pesquisa.bvsalud.org/global-literature-on-novel-coro...
Killing Two Birds with One Stone by Administration of Soluble ACE2: A Promising Strategy to Treat Both Cardiovascular Diseases and SARS-CoV-2 Infection https://www.mdpi.com/1999-4915/13/11/2243
Potent prophylactic and therapeutic efficacy of recombinant human ACE2-Fc against SARS-CoV-2 infection in vivo https://www.nature.com/articles/s41421-021-00302-0
Soluble ACE2 in SARS-CoV-2 infection https://www.nature.com/articles/s41581-021-00422-6
Zinc supplementation bolsters repurposed antivirals against SARS-CoV-2 https://www.news-medical.net/news/20210202/Zinc-supplementat...
COVID-19: Poor outcomes in patients with zinc deficiency https://www.sciencedirect.com/science/article/pii/S120197122...